Gods of Defense is a roguelike tower defense game set on a procedurally generated map. The God of your choosing stands on top of a temple at the center of the map. Corrupted enemies are trying to destroy the temple in waves, with every wave you get to banish the enemy gates further from the temple, thus revealing more of the map. The victory is achieved when you have destroyed all the Caves. After successfully defending against several waves you are awarded boons that give you new towers, bulk upgrades, and temporary advantages.